Treatment protocol

NiTi Brush for peri-implantitis example of protocol

The sequence below is an example of how the NiTi Brush is used in surgical peri-implantitis therapy, as practised by experienced clinicians. It is published by HANS Korea for orientation and is not a substitute for the Instructions for Use. Treatment decisions remain with the treating clinician.

1. Diagnosis

   Diagnose peri-implantitis and measure the depth of the pocket.

   

2. Select the brush for the case

   • NANO — for 1 to 2 thread(s) exposure
   • POCKET — for more than 2 threads exposure
   • POCKET SHORT — for molars
   

   Technical illustrations. The appearance of the delivered product may differ.

3. Sterilise before use

   • The NiTi Brush is supplied non-sterile — sterilise before every use
   • Use a sterile pouch and autoclave
   • 134 °C for 15 minutes
   

4. Rotate the NiTi Brush — polishing the surface

   Debridement & decontamination.

   • Use an implant motor
   • Rotating speed 600–1,200 rpm
   • Extensive external saline irrigation during brushing
   • Debride and clean the contaminated implant surface
   • Remove granulation tissue from the implant surface and the surrounding tissue in the same step

   Brushing time

   • About 2–3 minutes at 600 rpm, as reported in published clinical studies (Monje et al. 2023; 2025)
   • Follow the Instructions for Use; brushing time depends on the defect and the surface
   

   Before (left) and after (right) — clinical, macro and SEM

5. Chemical treatment — after brushing

   • As reported in the literature (clinician’s choice): a tetracycline-HCl solution applied to the debrided surface, e.g. one 250 mg capsule dissolved in 5 mL saline (50 mg/mL) for up to 5 minutes (Suh et al. 2003)
   • This concentration did not alter SLA surface microstructure in vitro (Seo et al. 2007)
   • In a recent controlled trial, tetracycline hydrochloride was applied for 2 minutes after 3% hydrogen peroxide (Monje et al. 2026)
   • Other agents (for example minocycline) are also described in the literature

   The agent and the protocol are a clinical decision. Please refer to the published literature rather than treating this example as a recommendation.

   

   What the published studies applied after brushing →

6. GBR — after chemical treatment

   Guided bone regeneration follows the decontamination and chemical steps. Refer to the references and literature for the reconstructive protocol.

   Clinical evidence
   

   One case from start to finish — diagnosis, debridement, graft and suture (top row), then the healed result at follow-up (bottom row)

   

   CBCT of the same implant — sagittal section (top) and 3D reconstruction (bottom)